Use of certain affinity NMDA antagonists as antidepressants (Assignee -- AstraZeneca AB)

26 ноября, 2002
Abstract: The invention relates to the use of certain pharmaceutical compounds as antidepressant agents. U.S. Patents via NewsEdge Corporation : Abstract: The invention relates to the use of certain pharmaceutical compounds as antidepressant agents. Ex Claim Text: Method of treating or preventing depression in a mammal which comprises administering to a person in need thereof a therapeutic effective amount of a compound having low affinity NMDA antagonist activity or a pharmaceutically acceptable salt thereof, where the compound is a compound of formula (I): ##STR2## wherein: R.sup.1 is pyridyl, phenyl or 4 fluorophenyl; R.sup.2 is phenyl or 4 flurophenyl; R.sup.3 hydrogen, C.sub.16 alkyl or methoxycarbonyl; R.sup.4 is hydrogen or methyl; and R.sup.5 is hydrogen or COCH.sub.2 NH.sub.2. Patent Number: 6479553 Issue Date: 2002 11 12 If you would like to purchase a copy of this patent, please call MicroPatent at 800-648-6787. Inventor(s): McCarthy, Dennis J. << Copyright ©2002 MicroPatent >>
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